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Celebrex Testimonials:
Celebrex works for me and my increasing ease of mobility. Still, I like a mad woman in the itching hands and bottom of my toes. I bite them, itch so much. I have a few places where I literally rubbed off the skin on your hands! It also helps with my hip arthritis. Other than side effects, it is a good medicine, but God knows what makes my heart or liver.
Testimonials:
I am able to walk every day, when I use Celebrex. My recent change in skin irritation on my hands, I is the adoption of this assessment. I'll have to look into it. But beyond that which could have no relationship, I am very satisfied with Celebrex. I tried, and others had the same results as I am with Celebrex ..
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Drug Name
Celebrex (Celecoxib)
Drug Uses
Celecoxib is used for relief of pain, fever, swelling, and tenderness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib does not prevent the progression or the type of arthritis. It reduces only the symptoms and signs of arthritis. Celecoxib was approved for patients with FAP family who had their colons removed. Celebrex and is approved for relief of acute pain and pain menstrual cramps (primary dysmenorrhea).
How to use
The lowest effective dose should be used for each patient. To manage osteoarthritis, the dose usually is 100 mg twice daily or 200 mg in a single dose. For rheumatoid arthritis, the dose is usually 100 or 200 mg twice a day. For acute pain or menstrual cramps, the dose is 400 mg in a single dose on the first day, followed by an additional 200 mg if needed, and then 200 mg twice daily as needed. For FAP, the recommended dose is 400 mg twice a day.
Drug Class and mechanism
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Celecoxib is a non-steroidal anti-inflammatory drugs (NSAIDs) used to treat arthritis, pain, menstrual cramps, and Colonic polyps. Prostaglandins are chemicals that are an important contribution to the inflammation of arthritis that causes pain, fever, swelling and tenderness. Celecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase 2), resulting in lower concentrations of prostaglandins. As a result, reduces the inflammation and accompanying pain, fever, swelling and tenderness. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine (at least in the short term treatment) and does not interfere with blood clotting. NSAIDs have been found to prevent formation and reduce the size of polyps in patients with genetic diseases, familial adenomatous polyposis (FAP). In FAP, patients develop numerous polyps in the colon, polyps and always become malignant. Only treatment of FAP requires removal of the entire colon. Celecoxib has been approved as adjunctive (secondary) treatment in patients with FAP. Cramping and pain during menstruation is due to prostaglandins, and blocking production of prostaglandins with celecoxib reduces the cramps and pain.
Missed Dose
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Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the regularly scheduled dose as directed. Do not take a double dose of this medicine unless your doctor instructs otherwise.
Storage
Capsules should be stored at 25 degrees C (77 degrees F). It is OK for short periods in temperatures between 15-30 ° C (59-86 ° F).
Warnings / Precautions
There are no restrictions on food, beverages, or activity while taking celecoxib unless otherwise directed by your doctor. Concomitant use of celecoxib with aspirin or other NSAIDs (eg ibuprofen, naproxen, etc.) May increase the occurrence of stomach and intestinal ulcers. Fluconazole (diflucan) increases the concentration of celecoxib in the body inhibits the breakdown of celecoxib in the liver. Therefore, treatment with celecoxib should be initiated at the lowest recommended dose in patients who are taking fluconazole. Celecoxib increases the concentration of lithium (Eskalith) in the blood by 17%. Therefore, lithium therapy should be closely monitored during and after therapy with celecoxib. The person taking the anticoagulant (blood thinner) warfarin (coumadin), should have their blood tested when the promotion or changing celecoxib treatment, particularly in the first few days of any change in anticoagulant activity. People who drink more than 3 alcoholic beverages a day, May be at increased risk of developing stomach ulcers when taking NSAIDs, and this May also be true with celecoxib. Celecoxib was not studied in pregnant women. In animal studies, doses that were twice the maximum recommended doses are harmful to the fetus. Celecoxib only be used in pregnant women when benefits outweigh the potential risk to the fetus. The use of celecoxib in nursing mothers is not evaluated.
Possible side effects
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Although stomach and intestinal ulcers occur with the use of celecoxib, their incidence is lower than other NSAIDs in short-term studies. Celecoxib does not interfere with platelet function and blood as a result, does not reduce clotting and lead to increased bleeding like other NSAIDs. Usually side effects are headache, abdominal pain, dyspepsia, diarrhea, nausea, flatulence and insomnia. Other side effects include fainting, kidney failure, heart failure, worsening hypertension, chest pain, ringing in the ears, deafness, stomach and intestinal ulcers, bleeding, blurred vision, anxiety, Photosensitivity, weight gain, water retention, flu-like symptoms, drowsiness and weakness . Allergic reactions can occur with celecoxib. Individuals who have developed allergic reactions (rash, itching, difficulty breathing) from sulfonamides (eg, butalbital), aspirin or other NSAIDs May experience an allergic reaction to celecoxib and should not take celecoxib.
More information
Tell your doctor immediately if you develop abdominal pain, tenderness, or discomfort, nausea, bloody vomit, bloody, black, or hesitation, chairs, unexplained weight gain, water retention and swelling, fatigue or drowsiness, skin rash, itching, yellowing of the skin or eyes, “flu-like” symptoms or unusual bruising or bleeding. These symptoms may be early signs of dangerous side effects. If you experience any of the following serious side effects, stop taking celecoxib and seek medical treatment or call your doctor immediately: an allergic reaction (difficulty breathing, closing of your throat, swelling of lips, tongue or face or hives). Other, less serious side effects May be more likely to occur. Continue to take celecoxib and talk to your doctor if you have bloating or diarrhea, dizziness, headaches or insomnia. Side effects other than those listed here, May also occur. Talk to your doctor about any side effect that seems unusual or that is especially boring.